The Lamborghini Murciélago is a sports car produced by Italian automaker Lamborghini. It is often referred to as a supercar and is Lamborghini's flagship and the halo car of the automaker's lineup.

The Murciélago is a high-performance two-door, two-seat coupé, powered by an evolution of the Lamborghini V12 engine. A roadster version of the car was introduced in 2004.

The Murciélago was introduced in 2001 for the 2002 model year as the successor to the famed Diablo supercar, and was the automaker's first new design in eleven years, as well as the first under the ownership of German automaker Audi. Continuing company tradition, the Murciélago was named for a famed Spanish fighting bull, and was styled by Peruvian-born Belgian Luc Donckerwolke, Lamborghini's head of design from 1998 to 2005.

The Murciélago is a four-wheel drive, mid-engined sports car. Its coupé body is especially low-slung, with its roof rising to just under four feet above the ground. The supercar features scissor doors, which contribute to its exotic image. 

First-generation Murciélagos, produced between 2001 and 2006, were powered by a 6.2-litre V12 which traces its roots back to the company's beginnings in the 1960s. The rear differential is integrated into the engine unit, and the four-wheel drive features a central viscous coupler. Power was sent to the wheels through a six-speed manual. The Murciélago possesses an independent double-wishbone suspension design, and features a combination of carbon-fiber and steel bodywork. The rear spoiler and the air scoops integrated into the car's shoulders are electromechanically activated, and fold out from the body at high speeds to aid aerodynamic performance and provide additional engine cooling, respectively.

The V12 engine in these cars produced just under 580 PS, a unit of power commonly used in Europe. The engine was capable of powering the car to a speed of 60 mph (97 km/h) in 3.8 seconds. The first-generation cars, equipped with the 6.2-litre V12, were produced between 2001 and 2006, and are known simply as Murciélago. Although subsequent versions of the Murciélago were designated with their engine output in PS, the original cars were not designated "LP 580" in line with the later convention.